logoRSD
arrowHome page
arrowServices
arrowProducts
arrowAchievements
arrowReferences
arrowContacts
arrowSite map

arrowReactor
arrowLaboratory
arrowWorkshop
arrowBNCT




BORON NEUTRON CAPTURE THERAPY
( BNCT)
 
The BNCT project at LVR-15 reactor of NRI for treatment of human brain gliomas is before start of clinical trials. A survey of present conditions is included, the attention is devoted to BNCT facility with epithermal neutron beam first of all. The different materials for filter composition were studied, the calculational methods have been used for the determination of neutron and gamma rays in the reactor geometry. Some configurations were experimentally verified. The effort for improvement of epithermal neutron beam parameters in configuration 1998 was concentrated to block of filters remodeling, improvement of collimator-shutter geometry, the choice of optimal reactor core edge configuration. Awaited results from experiment in June 1999 are described.
BNCT at LVR - 15 reactor
 
The BNCT interdisciplinary group in the Czech republic decided as a first priority to initiate the glioma clinical trial at the LVR reactor of NRI. The principal aim now is to prepare the Phase I trial, to establish maximum tolerated dose by healthy tissue when irradiating with BSH drug. The activity has been concentrated in this final stage also on improvement of the parameters of the beam. The treatment protocol was prepared and put forward to corresponding authorities for approval.
Epithermal neutron beam configuration 1998